Phenylbutazone and chromosomal damage.
نویسندگان
چکیده
منابع مشابه
Phenylbutazone and chromosomal damage.
Investigation of 44 paired test and control patients, all suffering from rheumatoid arthritis, following exposure to phenylbutazone (PBZ) and/or oxyphenbutazone (OPB), suggests that there is no significant increase in the level of chromosomal damage in lymphocytes. The control subjects comprised two series, one previously exposed to PBZ and/or OPB, but not for at least 1-5 years, and the other ...
متن کاملChromosomal studies in patients taking phenylbutazone.
In course of investigating a family for another purpose, an elderly woman was found to have a high proportion of grossly damaged chromosomes. During the preceding 15 months she had been taking phenylbutazone for osteoarthrosis. She had never had any external or internal radiation therapy, and the only other drug shewas taking was a 50mg. nembutal capsule each night. As there was no obvious expl...
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sterilisation there is a risk of infection. Diabetics commonly keep their syringes in spirit although similar practices have been abandoned in hospital, where sterile instruments are now stored dry. It would seem logical for diabetics to store their syringes-glass or plastic-in the same way. Thirty patients reported by Greenough et a13 used a single plastic syringe, stored dry in a domestic ref...
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Correspondence BMJORL 16 of the facilities provided, all general practitioners , paediatricians, and district medical officers in the county were circularized. They were informed of the existing provisions for the mentally handicapped in the county, and were advised that if they wished to refer such patients, and their parents, to the county medical officer, arrangements would be made for them ...
متن کاملImpact of DNA Damage on the Frequency of Sperm Chromosomal Aneuploidy in Normal and Subfertile Men
Background: Various frequencies of sperm aneuploidy are reported in sperms of subfertile patients compared to normal individuals. Moreover, sperm DNA damage is shown to be associated with male infertility. In this study, the rate of DNA damage and frequencies of aneuploidy in sperms of subfertile patients was investigated. Methods: Semen samples were obtained from healthy normal and subfertile ...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1975
ISSN: 0003-4967
DOI: 10.1136/ard.34.5.409